2-Phenylisobutyric acid

CAS: 826-55-1

Ref. 3D-FP26983

Product Information

• Name: 2-Phenylisobutyric acid
• Synonyms: a,a-Dimethylbenzeneacetic acida-Methylhydratropic acid2,2-Dimethyl-2-phenylacetic acid, 2,2-Dimethyl-2-phenylacetic acid, 2-Methyl-2-Phenylpropanoate, 2-Methyl-2-phenylpropionic acid, 2-Phenyl-2-methylpropionic acid, 2-Phenylisobutanoic acid, Benzeneacetic acid, α,α-dimethyl-, Hydratropic acid, α-methyl-, NSC 28952, NSC 29095, Th 4161, a,a-Dimethyl Phenyl Acetic Acid, alpha,alpha-Dimethyl phenyl Acetic Acid, α,α-Dimethylbenzeneacetic acid, α,α-Dimethylphenylacetic acid

Description

2-Phenylisobutyric acid is a colorless to white crystalline solid with a molecular weight of 218.29 g/mol and a melting point of 120-122 °C. It is soluble in water, but not in alcohol or ether. 2-Phenylisobutyric acid is used as an intermediate for pharmaceutical preparations and as a reagent for organic synthesis. It is also used to produce thiomorpholine, which has been shown to have anti-inflammatory properties and can be used in the treatment of bowel disease. Thiomorpholine reacts with acylation agents such as phosphorus pentachloride to form esters that are useful pharmaceuticals, including corticosteroids. 2-Phenylisobutyric acid has been shown to inhibit insulin resistance by reacting with reactive sites on the insulin receptor, thus preventing the binding of insulin molecules to their receptors on cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 164.2 g/mol
• Formula: C₁₀H₁₂O₂
• Purity: Min. 95%
• Color/Form: White to off-white solid.
• InChI: InChI=1S/C10H12O2/c1-10(2,9(11)12)8-6-4-3-5-7-8/h3-7H,1-2H3,(H,11,12)
• InChI key: InChIKey=YYEROYLAYAVZNW-UHFFFAOYSA-N
• SMILES: CC(C)(C(=O)O)c1ccccc1