2-Phenylisobutyric acid

CAS: 826-55-1

Ref. 3D-FP26983

Product Information

• Name: 2-Phenylisobutyric acid
• Synonyms: a,a-Dimethylbenzeneacetic acida-Methylhydratropic acid2,2-Dimethyl-2-phenylacetic acid
• Brand: Biosynth
• Description: 2-Phenylisobutyric acid is a colorless to white crystalline solid with a molecular weight of 218.29 g/mol and a melting point of 120-122 °C. It is soluble in water, but not in alcohol or ether. 2-Phenylisobutyric acid is used as an intermediate for pharmaceutical preparations and as a reagent for organic synthesis. It is also used to produce thiomorpholine, which has been shown to have anti-inflammatory properties and can be used in the treatment of bowel disease. Thiomorpholine reacts with acylation agents such as phosphorus pentachloride to form esters that are useful pharmaceuticals, including corticosteroids. 2-Phenylisobutyric acid has been shown to inhibit insulin resistance by reacting with reactive sites on the insulin receptor, thus preventing the binding of insulin molecules to their receptors on cells.

Chemical properties

• Molecular weight: 164.2 g/mol
• Formula: C₁₀H₁₂O₂
• Purity: Min. 95%
• Color/Form: White to off-white solid.
• InChI: InChI=1S/C10H12O2/c1-10(2,9(11)12)8-6-4-3-5-7-8/h3-7H,1-2H3,(H,11,12)
• InChI key: InChIKey=YYEROYLAYAVZNW-UHFFFAOYSA-N
• SMILES: CC(C)(C(=O)O)c1ccccc1