Pholcodine

CAS: 509-67-1

Ref. 3D-FP27013

Product Information

• Name: Pholcodine
• Synonyms: Morpholinylethylmorphine, (5Alpha,6Alpha)-17-Methyl-3-(2-Morpholin-4-Ylethoxy)-7,8-Didehydro-4,5-Epoxymorphinan-6-Ol, (5α,6α)-7,8-Didehydro-4,5-epoxy-17-methyl-3-[2-(4-morpholinyl)ethoxy]morphinan-6-ol, 3-[2-(4-Morpholinyl)ethyl]morphine, Biocalyptol, Codylin, Ethnine, Folcodin, Folcodine, Galenphol, Galphol, Glycodine, Hibernyl, Homocodeine, Memine, Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-17-methyl-3-[2-(4-morpholinyl)ethoxy]-, (5α,6α)-, Morphinan-6α-ol, 7,8-didehydro-4,5α-epoxy-17-methyl-3-(2-morpholinoethoxy)-, Morphine, 3-O-(2-morpholinoethyl)-, Morphine, O³-(2-morpholinoethyl)-, Neocodine, O-2-Morpholinoethylmorphine, O3-(2-morpholinoethyl)morphine, O³-(2-Morpholinoethyl)morphine, Pectolin, Pholcodine (PI), Pholtex, Tussokon, Tuxi Forte, Weifacodine, β-Morpholinylethylmorphine

Description

Pholcodine is a cough suppressant that is used to relieve the symptoms of dry, tickly coughs. It does not have any analgesic properties and should not be used for the treatment of acute bronchitis or asthma. The drug is available in three forms: pholcodine bitartrate, pholcodine citrate, and pholcodine hydrochloride. Pholcodine is a tertiary amine that binds to cell nuclei and has been shown to cause DNA damage as well as inhibit protein synthesis. The drug has been shown to produce long-term toxicity in rats, but its clinical relevance to humans is unknown. A fluorescence detector was used to measure the sensitivity of the drug in detecting low levels of antibodies against it in human serum by measuring the change in fluorescence intensity upon binding with an antibody.

• Brand: Biosynth

Chemical properties

• Molecular weight: 398.5 g/mol
• Formula: C₂₃H₃₀N₂O₄
• Purity: Min. 95%
• Color/Form: Powder