Phyllanthin

CAS: 10351-88-9

Ref. 3D-FP27032

Product Information

• Name: Phyllanthin
• Synonyms: (6S,10R,11aR,11bS)-9,10,11,11a-Tetrahydro-10-methoxy-8H-6,11b-methanofuro[2,3-c]pyrido[1,2-a]azepin-2(6H)-one(4b)-4-Methoxysecurina n-11-one(-)-Phyllanthine, 1,1'-[(2R,3R)-2,3-bis(methoxymethyl)butane-1,4-diyl]bis(3,4-dimethoxybenzene), 1,1'-[(2S,3S)-2,3-bis(methoxymethyl)butane-1,4-diyl]bis(3,4-dimethoxybenzene), 1,1′-[(2S,3S)-2,3-Bis(methoxymethyl)-1,4-butanediyl]bis[3,4-dimethoxybenzene], Benzene, 1,1′-[(2S,3S)-2,3-bis(methoxymethyl)-1,4-butanediyl]bis[3,4-dimethoxy-, Benzene, 1,1′-[2,3-bis(methoxymethyl)-1,4-butanediyl]bis[3,4-dimethoxy-, [S-(R*,R*)]-, Butane, 1,4-dimethoxy-2,3-diveratryl-, (2S,3S)-(+)-, NSC 619043, benzene, 1,1'-[(2R,3R)-2,3-bis(methoxymethyl)-1,4-butanediyl]bis[3,4-dimethoxy-

Description

Phyllanthin is a natural compound and its chemical structure is similar to that of the phytochemical ursolic acid. Phyllanthin has been shown to have anti-inflammatory, antioxidant, and anticancer properties in a number of studies. Phyllanthin also inhibits the enzyme activities of drug-metabolizing enzymes such as cytochrome P450 and glutathione S-transferase. The main biological effects of phyllanthin are related to the inhibition of growth factor-β1 (a cytokine) and toll-like receptor 4 signaling, which are involved in inflammatory bowel disease. Phyllanthin has minimal toxicity and can be used for chemotherapy or other treatments without side effects.

• Brand: Biosynth

Chemical properties

• Molecular weight: 418.52 g/mol
• Formula: C₂₄H₃₄O₆
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C24H34O6/c1-25-15-19(11-17-7-9-21(27-3)23(13-17)29-5)20(16-26-2)12-18-8-10-22(28-4)24(14-18)30-6/h7-10,13-14,19-20H,11-12,15-16H2,1-6H3/t19-,20-/m1/s1
• InChI key: InChIKey=KFLQGJQSLUYUBF-WOJBJXKFSA-N
• SMILES: COC[C@@H](Cc1ccc(OC)c(OC)c1)[C@@H](COC)Cc1ccc(OC)c(OC)c1