5a-Pregnane-3a,20a-diol
CAS: 566-58-5
Ref. 3D-FP27149
| 1mg | To inquire | ||
| 2mg | To inquire | ||
| 5mg | To inquire | ||
| 10mg | To inquire | ||
| 25mg | To inquire |
Product Information
- (3a,5a,20S)-Pregnane-3,20-diol
- (3alpha,5alpha,20S)-Prgnane-3,20-diol
- (3alpha,5alpha,20S)-pregnane-3,20-diol
- (3α,5α,20S)-Pregnane-3,20-diol
- 3α,20α-Dihydroxy-5α-pregnane
- Allopregnane-3alpha,20alpha-diol
- Allopregnane-3α,20α-diol
- Allopregnanediol
- Pregnane-3,20-diol, (3α,5α,20S)-
- Prgnane-3,20-diol, (3alpha,5alpha,20S)-
- See more synonyms
5a-Pregnane-3a,20a-diol is a gamma-aminobutyric acid (GABA) analogue that is used in the treatment of women with variegated hyperpigmentation. It has inhibitory properties on mutant enzymes such as disulfate reductase and other enzymes involved in the synthesis of prostaglandins. The drug binds to the enzyme GABA transaminase and this binding prevents the formation of GABA from glutamate. 5a-Pregnane-3a,20a-diol also inhibits the synthesis of prostaglandin E2 by binding to cyclooxygenase 2, leading to decreased inflammation and pain. 5a-Pregnane-3a,20a-diol is metabolized by glucuronidation or sulfation and excreted into bile or urine. This drug can also be hydrolyzed by dehydrogenases or other enzymes such as esterases.
Chemical properties
Technical inquiry about: 3D-FP27149 5a-Pregnane-3a,20a-diol
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