Product Information
Name:5a-Pregnane-3a,20a-diol
Controlled Product
Synonyms:
- (3a,5a,20S)-Pregnane-3,20-diol
Brand:Biosynth
Description:5a-Pregnane-3a,20a-diol is a gamma-aminobutyric acid (GABA) analogue that is used in the treatment of women with variegated hyperpigmentation. It has inhibitory properties on mutant enzymes such as disulfate reductase and other enzymes involved in the synthesis of prostaglandins. The drug binds to the enzyme GABA transaminase and this binding prevents the formation of GABA from glutamate. 5a-Pregnane-3a,20a-diol also inhibits the synthesis of prostaglandin E2 by binding to cyclooxygenase 2, leading to decreased inflammation and pain. 5a-Pregnane-3a,20a-diol is metabolized by glucuronidation or sulfation and excreted into bile or urine. This drug can also be hydrolyzed by dehydrogenases or other enzymes such as esterases.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:320.51 g/mol
Formula:C21H36O2
Purity:Min. 95%
Technical inquiry about: 5a-Pregnane-3a,20a-diol
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