Promazine hydrochloride

CAS: 53-60-1

Ref. 3D-FP27180

Product Information

• Name: Promazine hydrochloride
• Synonyms: N,N-Dimethyl-10H-phenothiazine-10-propanamine Hydrochloride, 10-(γ-Dimethylamino-n-propyl)phenothiazine hydrochloride, 10H-Phenothiazine-10-propanamine, N,N-dimethyl-, hydrochloride (1:1), 10H-Phenothiazine-10-propanamine, N,N-dimethyl-, monohydrochloride, Esparinal, Liranol, N,N-dimethyl-3-(10H-phenothiazin-10-yl)propan-1-amine hydrochloride (1:1), Phenothiazine, 10-[3-(dimethylamino)propyl]-, monohydrochloride, Prolactyl, Promazine HCl, Promazine monohydrochloride, Promwill, Propazin, Propazin (pharmaceutical), Propazine, Prozine, Sparine, Talofen

Description

Promazine hydrochloride is an amphiphilic phenothiazine drug that blocks postsynaptic dopaminergic receptors (D1, D2 and D4) in the mesolimbic and medullary chemoreceptor trigger zone (antipsychotic effects, decreasing stimulation of the vomiting centre). Promazine is an antagonist at serotonin 5HT receptors, exhibits anticholinergic activity by blocking alpha-1 adrenergic receptors and blocks histamine H1 and muscarinic receptors. Promazine is used for adults in the treatment of psychomotor agitation, to prevent and treat nausea and vomiting, to treat allergy symptoms. Promazine hydrochloride is also used in veterinary medicine especially in horses as a pre-anaesthetic agent. Promazine is showed to be among drugs that can be used as starting points for designing SARS-CoV proteinase inhibitors.

• Brand: Biosynth

Chemical properties

• Molecular weight: 320.88 g/mol
• Formula: C₁₇H₂₁ClN₂S
• Purity: Min. 95%
• Color/Form: White Powder