Product Information
Name:Propentofylline
Controlled Product
Synonyms:
- 3,7-Dihydro-3-methyl-1-(5-oxohexyl)-7-propyl-1H-purine-2,6-dioneHWA-285Albert-285
Brand:Biosynth
Description:Propentofylline is a drug that has been shown to be neuroprotective in experimental models of stroke and brain injury. It inhibits glutamate-induced neuronal death by inhibiting the activation of nuclear DNA, leading to suppression of nuclear factor kappa B (NF-κB) and toll-like receptor (TLR) signaling pathways. It also decreases activity in cyclic nucleotide phosphodiesterases, which are enzymes involved in the regulation of cellular energy metabolism. Propentofylline increases microglial motility, which may be due to its ability to increase neurotrophic factors such as basic fibroblast growth factor and nerve growth factor.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:306.36 g/mol
Formula:C15H22N4O3
Purity:Min. 95%
InChI:InChI=1S/C15H22N4O3/c1-4-8-18-10-16-13-12(18)14(21)19(15(22)17(13)3)9-6-5-7-11(2)20/h10H,4-9H2,1-3H3
InChI key:InChIKey=RBQOQRRFDPXAGN-UHFFFAOYSA-N
SMILES:CCCn1cnc2c1c(=O)n(CCCCC(C)=O)c(=O)n2C
Technical inquiry about: Propentofylline
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