N-(1-Pyrenyl) maleimide

CAS: 42189-56-0

Ref. 3D-FP27290

Product Information

• Name: N-(1-Pyrenyl) maleimide
• Synonyms: N-(1-Pyrenyl)maleimide1-(1-Pyrenyl)-1H-pyrrole-2,5-dione

Description

N-(1-Pyrenyl) maleimide is a fluorescent derivative of maleimide. It has been shown to bind to the ryanodine receptor in the mitochondrial membrane, which is a calcium-binding protein that regulates the release of calcium from the sarcoplasmic reticulum and influences cellular energy metabolism and reactive oxygen species production. N-(1-Pyrenyl) maleimide has also been shown to induce mitochondrial membrane potential collapse in human serum, which may be due to its ability to bind to terminal residues on proteins.

• Brand: Biosynth

Chemical properties

• Molecular weight: 297.31 g/mol
• Formula: C₂₀H₁₁NO₂
• Purity: Min. 95%
• InChI: InChI=1S/C20H11NO2/c22-17-10-11-18(23)21(17)16-9-7-14-5-4-12-2-1-3-13-6-8-15(16)20(14)19(12)13/h1-11H
• InChI key: InChIKey=YXKWRQLPBHVBRP-UHFFFAOYSA-N
• SMILES: O=C1C=CC(=O)N1c1ccc2ccc3cccc4ccc1c2c34