4-Pyridazinecarboxylic acid

CAS: 50681-25-9

Ref. 3D-FP27296

Product Information

• Name: 4-Pyridazinecarboxylic acid
• Synonyms: 1(2H)-Pyrazinecarboxylic acidPyrzine-4-carboxylic acid
• Brand: Biosynth
• Description: 4-Pyridazinecarboxylic acid is a salt that contains sodium. It is a white crystalline solid that is soluble in water, ethanol, and acetone. It has been shown to be effective against Leishmania species and Cryptococcus neoformans. 4-Pyridazinecarboxylic acid inhibits the growth of these fungi by binding to their cell membrane and inhibiting protein synthesis. 4-Pyridazinecarboxylic acid forms coordination complexes with metal ions that are involved in electron transfer reactions during the oxidative phosphorylation process. This leads to a decrease in ATP production and an increase in reactive oxygen species (ROS), which disrupts the function of macrophages and other phagocytic cells, leading to immunosuppression.

Chemical properties

• Molecular weight: 124.1 g/mol
• Formula: C₅H₄N₂O₂
• Purity: Min. 95%
• InChI: InChI=1S/C5H4N2O2/c8-5(9)4-1-2-6-7-3-4/h1-3H,(H,8,9)
• InChI key: InChIKey=JUSIWJONLKBPDU-UHFFFAOYSA-N
• SMILES: O=C(O)c1ccnnc1