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Pyrimethamine
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Pyrimethamine

CAS: 58-14-0

Ref. 3D-FP27346

10g
149.00 €
25g
222.00 €
50g
351.00 €
100g
493.00 €
250g
868.00 €
Estimated delivery in United States, on Tuesday 10 Dec 2024

Product Information

Name:
Pyrimethamine
Synonyms:
  • 5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidineChloridin
  • 2, 4-Diamino-5-(4'-chlorophenyl)-6-ethylpyrimidine
  • 2, 4-Diamino-5-(p-chlorophenyl)-6-ethylpyrimidine
  • 2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine
  • 2,4-Diamino-5-p-chlorophenyl-6-ethylpyrimidine
  • 4753 R.P.
  • 5-(4-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine
  • 5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine
  • 5-(P-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine
  • Bw 50-63
  • See more synonyms
  • Chloridin
  • Chloridine
  • Darachlor
  • Darapram
  • Daraprim
  • Daraprime
  • Diaminopyritamin
  • Erbaprelina
  • Khloridin
  • Malacid
  • Malocid
  • Malocide
  • Nsc 3061
  • Pirimecidan
  • Pirimetamin
  • Pirimetamina
  • Pyrimethamin
  • Pyrimethamine Base
  • Pyrimidine, 2,4-diamino-5-(p-chlorophenyl)-6-ethyl-
  • Rp 4753
  • Tindurin
  • Tinduring
  • Wr 2978
Description:

Pyrimethamine is an antimalarial agent that has been used in the treatment of various infectious diseases. Pyrimethamine is a folic acid antagonist which inhibits the synthesis of DNA and RNA by inhibiting the enzyme dihydrofolate reductase. The drug binds to sulfadiazine, a sulfa drug, which prevents its conversion to active form and thereby prevents bacterial growth. Pyrimethamine can be administered orally or intravenously. It exhibits low toxicity and is excreted in the urine as an inactive metabolite. In vitro assays have shown pyrimethamine to be effective against HIV-1 infection, but it is not active against other viruses such as herpes simplex virus and influenza virus.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
248.71 g/mol
Formula:
C12H13ClN4
Purity:
Min. 95%
Color/Form:
Powder
InChI:
InChI=1S/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17)
InChI key:
InChIKey=WKSAUQYGYAYLPV-UHFFFAOYSA-N
SMILES:
CCc1nc(N)nc(N)c1-c1ccc(Cl)cc1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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