rac-Propranolol hydrochloride

CAS: 318-98-9

Ref. 3D-FP27655

Product Information

• Name: rac-Propranolol hydrochloride
• Synonyms: 1[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol hydrochlorideAngilolApsolol(±)-Propranolol hydrochloride
• Brand: Biosynth

Description

Propranolol is a beta-adrenergic receptor antagonist that is used to treat high blood pressure, chest pain and heart failure. It also has been shown to be effective in the treatment of inflammatory bowel disease (IBD). Propranolol blocks the binding of proprotein convertase subtilisin/kexin type 9 (PCSK9) to its receptors, which inhibits the production of LDL cholesterol. In humans, propranolol is metabolized through hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The drug also has a synergic effect with other drugs such as erythromycin and phenobarbital. Propranolol binds to proteins in red blood cells and decreases diastolic pressure.

Chemical properties

• Molecular weight: 295.8 g/mol
• Formula: C₁₆H₂₂ClNO₂
• Purity: Min. 98%
• Color/Form: White Powder