2-Piperidin-4-yl-1H-benzoimidazole

CAS: 38385-95-4

Ref. 3D-FP32882

Product Information

• Name: 2-Piperidin-4-yl-1H-benzoimidazole
• Synonyms: 1H-benzimidazole, 2-(4-piperidinyl)-, 2-(4-Piperidinyl)-1H-benzimidazol, 2-(4-Piperidinyl)-1H-benzimidazole, 2-(4-Piperidyl)-1H-benzimidazole, 2-(Piperidin-4-yl)-1H-1,3-benzodiazole, 2-(Piperidin-4-yl)-1H-benzo[d]imidazole, 2-(Piperidin-4-yl)benzimidazole, 2-Piperidin-4-Yl-1H-Benzoimidazole, 4-(Benzimidazol-2-yl)piperidine
• CAS: 38385-95-4

Description

2-Piperidin-4-yl-1H-benzoimidazole (2PB) is a cholinergic drug that has been shown to inhibit the acetylcholine esterase enzyme. It has been shown to be effective in the treatment of Alzheimer's disease and cancer, as well as in the prevention of fluoroquinolone resistance. 2PB is an amine and can be found in a number of plants, such as tobacco and black pepper. It is also present in cannabis and some other plants. 2PB was synthesized by reacting 4-aminobenzaldehyde with 1-(2-piperidyl)benzene. The molecular modeling showed that 2PB may be used as a bioisostere for medicinal purposes.

• Brand: Biosynth

Chemical properties

• Molecular weight: 201.27 g/mol
• Formula: C₁₂H₁₅N₃
• Purity: Min. 95%
• InChI: InChI=1S/C12H15N3/c1-2-4-11-10(3-1)14-12(15-11)9-5-7-13-8-6-9/h1-4,9,13H,5-8H2,(H,14,15)
• InChI key: InChIKey=HBOGHPAOOWUTLB-UHFFFAOYSA-N
• SMILES: c1ccc2[nH]c(C3CCNCC3)nc2c1