CAS 38385-95-4

2-(Piperidin-4-yl)-1H-benzimidazole

Description:

2-(Piperidin-4-yl)-1H-benzimidazole is a chemical compound characterized by its unique structure, which includes a benzimidazole core substituted with a piperidine ring. This compound typically exhibits properties such as being a solid at room temperature, with moderate solubility in polar solvents due to the presence of nitrogen atoms in both the piperidine and benzimidazole moieties. It may display biological activity, making it of interest in medicinal chemistry, particularly in the development of pharmaceuticals. The presence of the piperidine group can influence its pharmacokinetic properties, such as absorption and distribution. Additionally, the compound may participate in hydrogen bonding and other intermolecular interactions, which can affect its reactivity and stability. Its CAS number, 38385-95-4, allows for easy identification in chemical databases and literature. Overall, 2-(Piperidin-4-yl)-1H-benzimidazole is a compound of interest for further research and potential applications in various fields, including drug discovery and development.

Formula: C₁₂H₁₅N₃

InChI: InChI=1/C12H15N3/c1-2-4-11-10(3-1)14-12(15-11)9-5-7-13-8-6-9/h1-4,9,13H,5-8H2,(H,14,15)

InChI key: InChIKey=HBOGHPAOOWUTLB-UHFFFAOYSA-N

SMILES: c1ccc2c(c1)nc(C1CCNCC1)[nH]2

Synonyms:

• 1H-benzimidazole, 2-(4-piperidinyl)-
• 2-(4-Piperidinyl)-1H-benzimidazol
• 2-(4-Piperidinyl)-1H-benzimidazole
• 2-(4-Piperidyl)-1H-benzimidazole
• 2-(Piperidin-4-yl)-1H-1,3-benzodiazole
• 2-(Piperidin-4-yl)-1H-benzo[d]imidazole
• 2-(Piperidin-4-yl)benzimidazole
• 2-Piperidin-4-Yl-1H-Benzoimidazole
• 4-(Benzimidazol-2-yl)piperidine

2-(4-Piperidinyl)benzimidazole

CAS: 38385-95-4

Formula: C₁₂H₁₅N₃

Purity: >98.0%(GC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 201.27

Ref: 3B-P2382

2-(Piperidin-4-yl)-1H-benzimidazole

CAS: 38385-95-4

Formula: C₁₂H₁₅N₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 201.2676

Ref: IN-DA0032UW

Bilastine Impurity 21

CAS: 38385-95-4

Formula: C₁₂H₁₅N₃

Molecular weight: 201.27

Ref: 4Z-B-1729

2-(4-Piperidyl)-1H-benzoimidazole

CAS: 38385-95-4

2-(4-Piperidyl)-1H-benzoimidazole

Formula: C₁₂H₁₅N₃

Purity: 98%

Molecular weight: 201.27

Ref: 54-OR1009782

2-(4-Piperidinyl)-1H-benzimidazole

CAS: 38385-95-4

Formula: C₁₂H₁₅N₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 201.273

Ref: 10-F077904

2-Piperidin-4-yl-1H-benzimidazole

Controlled Product

CAS: 38385-95-4

Applications 2-Piperidin-4-yl-1H-benzimidazole is used as a reagent in the synthesis of 3-amino-1-(5-indanyloxy)-2-propanol derivatives as potent sodium channel blockers for the treatment of ischemic stroke. Also used as a reagent in the synthesis of 2,3,5-trisubstituted pyridine derivatives as potent Akt1/Akt2 dual inhibitors.
References Seki, M., et al.: Chem. Pharm. Bull., 60, 488 (2012); Zhao, Z., et al.: Bioorg. Med. Chem. Lett., 15, 905 (2005)

Formula: C₁₂H₁₅N₃

Color and Shape: Neat

Molecular weight: 201.27

Ref: TR-P482075

Bilastine Impurity 17

CAS: 38385-95-4

Formula: C₁₂H₁₅N₃

Molecular weight: 201.27

Ref: ST-EA-CP-B13024