1,10-Phenanthroline monohydrate
CAS: 5144-89-8
Ref. 3D-FP34903
| 1kg | 1,449.00 € | ||
| 50g | 168.00 € | ||
| 100g | 260.00 € | ||
| 250g | 452.00 € | ||
| 500g | 818.00 € |
Product Information
- 1,10-Phenanthroline 1,10-Phenanthroline hydrate E2
- 1,10-Phenanthroline Hydrate (1:1)
- 1,10-Phenanthroline hydrate
- 4,5-Phenanthroline monohydrate
- Orthophenanthroline Monohydrate
- o-Phenanthroline,Monohydrate
1,10-Phenanthroline monohydrate is a metal chelate that binds to DNA by hydrogen bonds. It has been shown to have an intramolecular hydrogen and a linear calibration curve with a coefficient of determination (r2) of 0.998. The rate constant for the reaction of 1,10-phenanthroline monohydrate with DNA is 5.00 x 10 M-1 s-1 at 25°C in water and pH 7.4 buffer. The coordination geometry for 1,10-phenanthroline monohydrate is octahedral with the axial ligands occupying the equatorial positions and the equatorial ligands occupying the axial positions. This compound has been shown to be active against HL-60 cells, which causes cancerous transformations in vitro. Fluorescence spectrometry data shows that 1,10-phenanthroline monohydrate can bind to DNA in vitro but not in vivo.
Chemical properties
Technical inquiry about: 3D-FP34903 1,10-Phenanthroline monohydrate
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