(4-Pyridyl)acetone

CAS: 6304-16-1

Ref. 3D-FP36055

Product Information

• Name: (4-Pyridyl)acetone
• Synonyms: 1-(4-Pyridinyl)-2-propanone, 1-(4-Pyridyl)-2-acetone, 1-(4-Pyridyl)-2-propanone, 1-(4-Pyridyl)acetone, 1-(Pyridin-4-Yl)Propan-2-One, 1-(Pyridin-4-yl)acetone, 2-Propanone, (4-pyridyl)-, 2-Propanone, 1-(4-pyridinyl)-, 2-Propanone, 1-(4-pyridyl)-, 4-(2-Oxopropyl)pyridine, 4-Acetonylpyridine, 4-Pyridinylacetone, 4-Pyridylacetone, Methyl 4-pyridylmethyl ketone, NSC 42613

Description

4-Pyridylacetone (4PA) is a chloride channel blocker that blocks the ion channels in muscle cells, leading to decreased levels of chloride ions. This leads to the inhibition of the release of pro-inflammatory cytokines and therefore has potential as a treatment for inflammatory diseases such as congestive heart failure, chronic obstructive pulmonary disease, and atherosclerosis. 4PA also inhibits the activation of macrophages by LPS, which may be beneficial in treating autoimmune disorders. Molecular docking analysis has shown that 4PA can bind to aminomalonamide, a drug used to treat myeloma cancer, suggesting that it could be used as an alternative treatment.

• Brand: Biosynth

Chemical properties

• Molecular weight: 135.16 g/mol
• Formula: C₈H₉NO
• Purity: Min. 98 Area-%
• Color/Form: Colorless Yellow Clear Liquid
• InChI: InChI=1S/C8H9NO/c1-7(10)6-8-2-4-9-5-3-8/h2-5H,6H2,1H3
• InChI key: InChIKey=ILRVKOYYFFNXDB-UHFFFAOYSA-N
• SMILES: CC(=O)Cc1ccncc1