Plerixafor

CAS: 110078-46-1

Ref. 3D-FP36846

Product Information

• Name: Plerixafor
• Synonyms: 1,1'-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecaneAMD3100, 1,1'-(Benzene-1,4-Diyldimethanediyl)Bis(1,4,8,11-Tetraazacyclotetradecane), 1,1'-(Benzene-1,4-Diyldimethanediyl)Bis-1,4,8,11-Tetraazacyclotetradecane Octahydrobromide Dihydrate, 1,1'-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane, 1,1'-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane]Octahydrobromide Dihydrate, 1,1′-Xylyl bis-1.4,8,11 tetraaza cyclotetradecane, 1,4,8,11-Tetraazacyclotetradecane, 1,1′-[1,4-phenylenebis(methylene)]bis-, 1,4-Bis((1,4,8,11-Tetraazacyclotetradecan-1-Yl)Methyl)Benzene, 1-[[4-(1,4,8,11-Tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane, Amd 3100, Jkl 169, Jm 3100, Mozobil, Sdz Sid 791

Description

Initially identified as a selective inhibitor of HIV-1 and HIV-2 replication. This activity was ascribed to the specific binding to chemokine receptor CXCR4 and inhibition of its signaling downstream, mediated by SDF-1. Antagonizes binding of CXCL12 to CXCR4, inducing mobilization of hematopoietic progenitor cells that is enhanced in synergy with G-CSF.

• Brand: Biosynth

Chemical properties

• Molecular weight: 502.78 g/mol
• Formula: C₂₈H₅₄N₈
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C28H54N8/c1-9-29-15-17-31-13-3-21-35(23-19-33-11-1)25-27-5-7-28(8-6-27)26-36-22-4-14-32-18-16-30-10-2-12-34-20-24-36/h5-8,29-34H,1-4,9-26H2
• InChI key: InChIKey=YIQPUIGJQJDJOS-UHFFFAOYSA-N
• SMILES: c1cc(CN2CCCNCCNCCCNCC2)ccc1CN1CCCNCCNCCCNCC1