4-Piperidinopiperidine

CAS: 4897-50-1

Ref. 3D-FP37276

Product Information

• Name: 4-Piperidinopiperidine
• Synonyms: 1,4'-Bipiperidine, 1,4'-Bipiperidinium, 1-(4-Piperidyl)piperidine, 1-(Piperidin-4-yl)piperidine, 4-(1-Piperidino)piperidine, 4-(1-Piperidinyl)Piperidine, [1,4′]Bipiperidinyl

Description

4-Piperidinopiperidine is a potential inhibitor of the enzyme, fatty acid synthase (FASN), which catalyzes the conversion of acetyl-CoA to malonyl-CoA. This reaction is important for the production of palmitic acid and other long chain fatty acids. 4-Piperidinopiperidine has been shown to inhibit FASN activity in a dose dependent manner with an IC50 value of 0.1 mM. The inhibition was not reversible and covalent adducts were formed with lysine residues on the protein surface. 4-Piperidinopiperidine has been shown to bind to DNA templates in an agarose gel electrophoresis assay, suggesting that this drug may be useful as a template molecule for therapeutic purposes.

• Brand: Biosynth

Chemical properties

• Molecular weight: 168.28 g/mol
• Formula: C₁₀H₂₀N₂
• Purity: Min. 95%
• InChI: InChI=1S/C10H20N2/c1-2-8-12(9-3-1)10-4-6-11-7-5-10/h10-11H,1-9H2
• InChI key: InChIKey=QDVBKXJMLILLLB-UHFFFAOYSA-N
• SMILES: C1CCN(C2CCNCC2)CC1