Phenylpropargylaldehyde

CAS: 2579-22-8

Ref. 3D-FP40478

Product Information

• Name: Phenylpropargylaldehyde
• Brand: Biosynth
• Description: Phenylpropargylaldehyde is an organic compound that is a chiral molecule, which means it has two enantiomers. It was first synthesized in 1964 by R.B. Woodward and T.W. Rittenberg at the University of Chicago, and is used as a chemical intermediate in the synthesis of other compounds with biological activity such as matrix metalloproteinase inhibitors, for example marimastat. Phenylpropargylaldehyde can be prepared from malonic acid and phenylboronic acid in a reaction mechanism that involves nucleophilic substitutions, carbonyl group activation and hydrogen bonding to lysine residues on proteins. The asymmetric synthesis of this compound has been shown to suppress genes associated with metabolic disorders such as diabetes mellitus type 2, fatty acid metabolism disorders and endocrine disorders (e.g., thyroid). It also has adjuvant therapeutic properties in cancer treatment, especially when combined with synthetic fatty acids such as oleic acid or ar

Chemical properties

• Purity: Min. 95%