5alpha-Pregnane-3,20-dione

CAS: 566-65-4

Ref. 3D-FP40764

Product Information

• Name: 5alpha-Pregnane-3,20-dione
• Synonyms: (+)-(5α)-Pregnane-3,20-dione, 3,20-Allopregnanedione, 3,20-Dioxo-5α-pregnane, 5-Alpha-Dihydroprogesterone, 5-Alpha-Pregnane-3,20-Dione, 5-Α-Pregnane-3,20-Dione, 5-Α-Pregnano-3,20-Diona, 5-α-Pregnan-3,20-dion, 5A-pregnane-3-20-dione-allo, 5α-Dihydro-P4, 5α-Dihydroprogesterone, 5α-Pregnanedione, Nsc 18319, Pregnan-3,20-dione, Pregnane-3,20-dione, (5α)-

Description

5alpha-Pregnane-3,20-dione is a naturally occurring sex steroid hormone. It is produced by the ovaries and testes in humans and other mammals, as well as by the adrenal glands in small amounts. 5alpha-Pregnane-3,20-dione has been shown to inhibit the enzyme activity of hepatic microsomes that are responsible for the conversion of progesterone to 17beta-hydroxyprogesterone (17betaOHP). This inhibition is due to its ability to bind to glucocorticoid receptors. 5alpha-Pregnane-3,20-dione also inhibits fatty acid synthesis in liver cells. The drug's antiproliferative effects on ovarian cells are mediated through a number of mechanisms including transcriptional repression of progesterone receptors and estradiol benzoate binding sites on DNA. 5alpha-Pregnane-3,20-dione has been shown to have an optimal

• Brand: Biosynth

Chemical properties

• Molecular weight: 316.48 g/mol
• Formula: C₂₁H₃₂O₂
• Purity: Min. 95%
• Color/Form: Powder