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Proguanil
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Proguanil

CAS: 500-92-5

Ref. 3D-FP41719

1g
514.00 €
50mg
136.00 €
100mg
172.00 €
250mg
247.00 €
500mg
363.00 €
Estimated delivery in United States, on Tuesday 21 Jan 2025

Product Information

Name:
Proguanil
Synonyms:
  • N1-(4-Chlorophenyl)-N5-isopropylbiguanideN-(4-Chlorophenyl)-N'-isopropylimidodicarbonimidic diamide
  • 1-(4-Chlorophenyl)-5-Isopropylbiguanide
  • 1-(p-Chlorophenyl)-5-isopropylbiguanide
  • 1-Isopropyl-5-(4-chlorophenyl)biguanide
  • Biguanide, 1-(p-chlorophenyl)-5-isopropyl-
  • Bigumal
  • Chlorguanid
  • Chlorguanide
  • Chloroguanide
  • Imidodicarbonimidic diamide, N-(4-chlorophenyl)-N'-(1-methylethyl)-
  • See more synonyms
  • Ips 07004
  • N-(4-Chlorophenyl)-N′-(1-methylethyl)imidodicarbonimidic diamide
  • N1-p-Chlorophenyl-N5-isopropylbiguanide
  • N<sup>1</sup>-p-Chlorophenyl-N<sup>5</sup>-isopropylbiguanide
  • Paludrin
  • Proguanil hydrochloride
Description:

Proguanil is a drug that belongs to the class of p450 inhibitors. It is used to prevent and treat malaria, especially in areas where resistance to chloroquine has emerged. Proguanil inhibits microbial growth by inhibiting the activity of the enzyme p450, which is involved in the synthesis of cholesterol and other sterols. This inhibition prevents the production of these compounds, which are necessary for bacterial cell walls. Proguanil also blocks lymphocyte transformation and polymerase chain reactions (PCR) by binding to DNA-dependent RNA polymerase. Proguanil has been shown to be effective against infectious diseases such as malaria, infectious diarrhoea, and typhoid fever. The drug has been shown to have pharmacokinetic properties that differ depending on the dose and duration of treatment, with a high clearance rate at low doses but a lower clearance rate at higher doses. Proguanil does not bind well to albumin or human erythrocytes,

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
253.73 g/mol
Formula:
C11H16ClN5
Purity:
Min. 95%
Color/Form:
Solid
InChI:
InChI=1S/C11H16ClN5/c1-7(2)15-10(13)17-11(14)16-9-5-3-8(12)4-6-9/h3-7H,1-2H3,(H5,13,14,15,16,17)
InChI key:
InChIKey=SSOLNOMRVKKSON-UHFFFAOYSA-N
SMILES:
CC(C)/N=C(N)/N=C(\N)Nc1ccc(Cl)cc1
MDL:
Melting point:
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EINECS:
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HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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