Product Information
Name:LDN 193189
Synonyms:
- 4-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline
Brand:Biosynth
Description:Inhibitor of ALK1, ALK2, ALK3 and ALK6 kinases and bone morphogenetic protein (BMP) pathway. LDN 1931189 is a dorsomorphin derivative that inhibits BMP-mediated activation of Smad, Akt and p38 signalling. LDN 193189 promotes differentiation of human pluripotent cells into PAX6+ anterior neural ectoderm. In combination with basic fibroblast growth factor (FGF2), LDN 193189 promotes differentiation of mouse pluripotent stem cells into inner ear sensory epithelium.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:406.48 g/mol
Formula:C25H22N6
Purity:Min. 98 Area-%
Color/Form:Powder
InChI:InChI=1S/C25H22N6/c1-2-4-24-22(3-1)21(9-10-27-24)23-16-29-31-17-19(15-28-25(23)31)18-5-7-20(8-6-18)30-13-11-26-12-14-30/h1-10,15-17,26H,11-14H2
InChI key:InChIKey=CDOVNWNANFFLFJ-UHFFFAOYSA-N
SMILES:c1ccc2c(-c3cnn4cc(-c5ccc(N6CCNCC6)cc5)cnc34)ccnc2c1
Technical inquiry about: LDN 193189
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