D-Phenylalanyl-prolyl-arginyl chloromethyl ketone

CAS: 71142-71-7

Ref. 3D-FP46717

Product Information

• Name: D-Phenylalanyl-prolyl-arginyl chloromethyl ketone
• Synonyms: 13: PN: WO03076461 PAGE: 51 claimed protein, <span class="text-smallcaps">D</smallcap>-Phenylalanyl-<smallcap>L</smallcap>-prolyl-<smallcap>L</span>-arginyl chloromethyl ketone, <span class="text-smallcaps">D</smallcap>-Phenylalanyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(2-chloroacetyl)butyl]-<smallcap>L</span>-prolinamide, <span class="text-smallcaps">D</span>-Phenylalanyl-prolyl-arginyl chloromethyl ketone, <span class="text-smallcaps">L</smallcap>-Prolinamide, <smallcap>D</span>-phenylalanyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(2-chloroacetyl)butyl]-, <span class="text-smallcaps">L</smallcap>-Prolinamide, <smallcap>D</span>-phenylalanyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(chloroacetyl)butyl]-, <span class="text-smallcaps">L</smallcap>-Prolinamide, <smallcap>D</span>-phenylalanyl-N-[4-[(aminoiminomethyl)amino]-1-(chloroacetyl)butyl]-, (S)-, D-Phe-pro-arg CH2Cl, D-Phenylalanine-proline-arginine methyl chloride, D-phenylalanyl-N-{(1S)-1-(chloroacetyl)-4-[(diaminomethylidene)amino]butyl}-L-prolinamide, H-D-Phe-Pro-Arg-Chloromethylketone Trifluoroacetate Salt, L-Prolinamide, D-phenylalanyl-N-(4-((aminoiminomethyl)amino)-1-(chloroacetyl)butyl)-, (S)-, Pebac, Phe-pro-arg-methyl chloride, Phenylalanyl-prolyl-arginine methyl chloride, Ppack

Description

D-Phenylalanyl-prolyl-arginyl chloromethyl ketone is a chemical compound that inhibits the proteolytic activity of serine proteases. It binds to the thrombin receptor on the surface of cells and prevents activation of fibrinogen by thrombin, which is an enzyme that promotes clotting. D-Phenylalanyl-prolyl-arginyl chloromethyl ketone also blocks platelet aggregation and has shown an ability to induce muscle cell proliferation. This drug has been used in pharmacological experiments as an inhibitor binding agent.

• Brand: Biosynth

Chemical properties

• Molecular weight: 450.96 g/mol
• Formula: C₂₁H₃₁ClN₆O₃
• Purity: Min. 90 Area-%
• Color/Form: Powder