Z-Phe-Arg-AMC·HCl

CAS: 65147-22-0

Ref. 3D-FP47305

Product Information

• Name: Z-Phe-Arg-AMC·HCl
• Synonyms: Purity Limit? 99% (TLC)
• Brand: Biosynth
• Description: Z-Phe-Arg-AMC·HCl is a fluorescent substrate for proteolytic enzymes. It has been shown to be a potent inhibitor of human immunoglobulin (Ig) secretion and protein synthesis in proximal tubules of the kidney, but this inhibition is not seen in the presence of other proteases. Z-Phe-Arg-AMC·HCl also inhibits the activity of soybean trypsin and hemolytic activity. This compound also has an optimum pH of 7.5 and is characterized by intermolecular hydrogen bonding as well as hydroxyl group interactions with enzyme active sites.

Chemical properties

• Molecular weight: 649.14 g/mol
• Formula: C₃₃H₃₆N₆O₆·HCl
• Purity: Min. 95%