Z-Phe-Arg-AMC·HCl

CAS: 65147-22-0

Ref. 3D-FP47305

Product Information

• Name: Z-Phe-Arg-AMC·HCl
• Synonyms: Purity Limit? 99% (TLC), 3095V, 5: PN: WO2004106541 PAGE: 15 claimed protein, <span class="text-smallcaps">L</smallcap>-Argininamide, N-[(phenylmethoxy)carbonyl]-<smallcap>L</span>-phenylalanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-, Benzyloxycarbonylphenylalanylarginine 4-methyl-7-coumarylamide, Carbobenzoxy-<span class="text-smallcaps">L</smallcap>-phenylalanyl-<smallcap>L</span>-arginine-4-methylcoumaryl-7-amide, N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</smallcap>-phenylalanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-<smallcap>L</span>-argininamide, Z-Phe-Arg-AMC, Z-Phe-Arg-AMC . HCl, benzyl [(2S)-1-({(2S)-5-[(diaminomethylidene)amino]-2-[(4-methyl-2-oxo-2H-chromen-7-yl)amino]pentanoyl}amino)-1-oxo-3-phenylpropan-2-yl]carbamate
• CAS: 65147-22-0

Description

Z-Phe-Arg-AMC·HCl is a fluorescent substrate for proteolytic enzymes. It has been shown to be a potent inhibitor of human immunoglobulin (Ig) secretion and protein synthesis in proximal tubules of the kidney, but this inhibition is not seen in the presence of other proteases. Z-Phe-Arg-AMC·HCl also inhibits the activity of soybean trypsin and hemolytic activity. This compound also has an optimum pH of 7.5 and is characterized by intermolecular hydrogen bonding as well as hydroxyl group interactions with enzyme active sites.

• Brand: Biosynth

Chemical properties

• Molecular weight: 649.14 g/mol
• Formula: C₃₃H₃₆N₆O₆·HCl
• Purity: Min. 95%