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5-Pyridin-4-yl-2H-pyrazol-3-ylamine
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5-Pyridin-4-yl-2H-pyrazol-3-ylamine

CAS: 91912-53-7

Ref. 3D-FP51268

1g
349.00 €
100mg
137.00 €
250mg
163.00 €
500mg
243.00 €
Estimated delivery in United States, on Tuesday 10 Dec 2024

Product Information

Name:
5-Pyridin-4-yl-2H-pyrazol-3-ylamine
Synonyms:
  • 1H-pyrazol-5-amine, 3-(4-pyridinyl)-
Description:

5-Pyridin-4-yl-2H-pyrazol-3-ylamine is a potent inhibitor of b-raf, a protein kinase that is involved in the regulation of cell proliferation and differentiation. It is used as a research tool for studying the role of b-raf in cancer. 5-Pyridin-4-yl-2H-pyrazol-3-ylamine has been shown to have similar activity to other inhibitors of bRaf. It binds to the ATP binding site on bRaf and prevents phosphorylation of serine residues in the activation loop by ATP. This inhibition prevents activation of the kinase and reduces tumor growth in cancer models.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
160.18 g/mol
Formula:
C8H8N4
Purity:
Min. 95%
Color/Form:
White/Off-White Solid
InChI:
InChI=1S/C8H8N4/c9-8-5-7(11-12-8)6-1-3-10-4-2-6/h1-5H,(H3,9,11,12)
InChI key:
InChIKey=MDRGSALNBWSYJX-UHFFFAOYSA-N
SMILES:
Nc1cc(-c2ccncc2)[nH]n1
MDL:
Melting point:
Boiling point:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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