(Phenylthio)acetic Acid
CAS: 103-04-8
Ref. 3D-FP61245
10g | To inquire | ||
25g | To inquire | ||
50g | To inquire | ||
100g | To inquire | ||
250g | To inquire |
Product Information
- (Phenylmercapto)acetic AcidS-Phenylthioglycolic AcidThiophenoxyacetic Acid
- (Phenylsulfanyl)Acetate
- (Phenylsulfanyl)Acetic Acid
- (S-Phenylmercapto)acetic acid
- 2-(Phenylsulfanyl)acetic acid
- 2-(Phenylthio)acetic acid
- Acetic acid, (phenylthio)-
- Acetic acid, 2-(phenylthio)-
- Carboxymethyl phenyl sulfide
- NSC 9582
- See more synonyms
- Phenylmercaptoacetic acid
- Phenylmercaptoacetic acid~S-Phenylthioglycolic acid~Thiophenoxyacetic acid
- Phenylthioglycolic acid
- Thiophenoxyacetic acid
- phenylethanethioic S-acid
- α-Carboxythioanisole
- (Phenylthio)acetic acid
Phenylthioacetic acid is a blood disorder drug that is used to treat high blood pressure and heart failure. It belongs to the group of drugs called thiocarboxylic acids. The reaction mechanism of phenylthioacetic acid involves the loss of hydrogen sulfide, which occurs by an addition-elimination reaction with hydroxide ions. Phenylthioacetic acid also has antihypertensive activity and inhibits malonic acid synthesis in the mitochondria by blocking the oxidation of malonyl-CoA. This drug binds to human serum albumin and consequently has a low therapeutic index, making it unsuitable for use in patients with liver or kidney disease. Structural data shows that phenylthioacetic acid exists as a zwitterion at physiological pH and that its asymmetric carbon atom is bound to two different groups: pyridine nitrogen (N) and an acyl chain. X-ray crystal structures show that the car
Chemical properties
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