Periplocin

CAS: 13137-64-9

Ref. 3D-FP63150

Product Information

• Name: Periplocin
• Synonyms: (3β,5β)-3-[(2,6-Dideoxy-4-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-3-O-methyl-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-5,14-dihydroxycard-20(22)-enolide, (3β,5β)-3-[(2,6-dideoxy-4-O-β-D-glucopyranosyl-β-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxycard-20(22)-enolide, Brn 0075742, Card-20(22)-enolide, 3-((2,6-dideoxy-4-O-beta-D-glucopyranosyl-3-O-methyl-beta-D-ribo-hexopyranosyl)oxy)-5,14-dihydroxy-, (3-beta,5-beta)-, Card-20(22)-enolide, 3-[(2,6-dideoxy-4-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-3-O-methyl-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-, (3β,5β)-, Glucoperiplocymarin, Periplogenin + D-cymarose + D-glucose, Periplogenin + D-cymarose + D-glucose [German], Periplogenin 3-O-[β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→4)-β-<smallcap>D</span>-cymaropyranoside], Periplogenin 3-O-[β-D-glucopyranosyl-(1→4)-β-D-cymaropyranoside], Card-20(22)-enolide, 3-[(2,6-dideoxy-4-O-β-D-glucopyranosyl-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-, (3β,5β)-, (3β,5β)-3-[(2,6-Dideoxy-4-O-β-D-glucopyranosyl-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxycard-20(22)-enolide, Periplocoside

Description

Periplocin is a natural compound that has been extracted from rhizoma gastrodiae and radix notoginseng. It inhibits cell proliferation by targeting the bcl-2 protein, which is a cell survival protein. Periplocin suppresses the expression of bcl-2 protein and induces G1 phase arrest in human squamous cell cancer cells. Periplocin also has antiinflammatory effects, which may be due to its inhibition of toll-like receptor 4 (TLR4).

• Brand: Biosynth

Chemical properties

• Molecular weight: 696.82 g/mol
• Formula: C₃₆H₅₆O₁₃
• Purity: Min. 95%
• Color/Form: White Powder