Product Information
- b-D-Glucopyranoside, (3b,22a,25R)-26-(b-D-glucopyranosyloxy)-22-hydroxyfurost-5-en-3-yl 2-O-(6-deoxy-a-L-mannopyranosyl)-, 4-(hydrogensulfate), monosodium salt (9CI)
- 26-O-b-glucopyranosyl-22a-hydroxy-(25R)-furost-5-ene-3b,26-diol-3-O- a-rhamnopyranosyl-(1® 2)-b-4-O-sulfoglucopyranoside sodium salt
Prototribestin is a saponin that has been shown to have anti-inflammatory properties. Prototribestin was isolated from the plant Tribulus terrestris, which grows in India. Prototribestin has been shown to inhibit inflammatory enzymes such as phospholipase A2, cyclooxygenase (COX-1 and COX-2), lipoxygenase, and nitric oxide synthase. Prototribestin also inhibits the production of proinflammatory prostaglandins and leukotrienes, while increasing the production of anti-inflammatory prostaglandins. Prototribestin also inhibits TNF-α and IL-1β induced expression of ICAM-1 and VCAM-1 in endothelial cells.
Chemical properties
Technical inquiry about: 3D-FP65585 Prototribestin
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