Product Information
- 2,N-Diphenylacetamide
- N,2-diphenylacetamide
2-Phenyl-N-phenylacetamide is an amide that is a potent inhibitor of cholesterol acyltransferase. It has been shown to be effective in animal models of insulin resistance and hypertension, as well as in humans. 2-Phenyl-N-phenylacetamide inhibits the activity of cholesterol acyltransferase by competitive inhibition and thereby reduces the production of triglycerides. This drug also inhibits the synthesis of phospholipids and bile acids, which are important for fat digestion. 2-Phenyl-N-phenylacetamide reacts with phosphorus pentoxide to form phenoxyacetic acid, which is hydrolyzed to phenoxyacetate and phenol. The hydroxy group on phenol reacts with aryl halides to form aryl esters. These reactions lead to the formation of divalent hydrocarbon intermediates such as malonic acid, which can be used for energy production through oxidation or as precursors
Chemical properties
Technical inquiry about: 3D-FP66190 2-Phenyl-N-phenylacetamide
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