(-)-Perillyl alcohol

CAS: 536-59-4

Ref. 3D-FP70326

Product Information

• Name: (-)-Perillyl alcohol
• Synonyms: (-)-p-Mentha-1,8-diene-7-ol, (4-Prop-1-en-2-ylcyclohexen-1-yl)methanol, (±)-Perillyl alcohol, 1-Cyclohexene-1-methanol, 4-(1-methylethenyl)-, 4-(1-Methylethenyl)-1-cyclohexene-1-methanol, 4-Isopropenyl-1-cyclohexene-methanol, 4-Isopropenyl-1-cyclohexenylmethanol, 4-Isopropenylcyclohex-1-En-1-Ylmethanol, Dihydro cuminyl alcohol, NSC 641066, Perilla alcohol, Perillic alcohol, Perillol, [(4S)-4-(prop-1-en-2-yl)cyclohex-1-en-1-yl]methanol, [4-(Prop-1-En-2-Yl)Cyclohex-1-En-1-Yl]Methanol, dl-Perillyl alcohol, p-Mentha-1,8-dien-7-ol

Description

(-)-Perillyl alcohol is a natural compound found in the essential oils of some plants. It has been shown to have potential anticancer activity, and is currently being studied for possible clinical use. (-)-Perillyl alcohol binds to the α1 subunit of DNA polymerase in the cancer cells and inhibits enzyme activities. This binding prevents the duplication of DNA and cell division, leading to cell death. In addition, (-)-perillyl alcohol has been shown to inhibit protein synthesis and alter morphology in murine hepatoma cells. (-)-Perillyl alcohol also binds to cell nuclei, where it alters gene expression by affecting transcription rates. The binding of (-)-perillyl alcohol also causes an increase in the rate of microextraction from solid phase surfaces due to its polar character.
-(-)-Perillyl alcohol has been shown to be more effective at inhibiting mouse tumors than wild-type strains when used as an experimental model for human osteosarcoma cells

• Brand: Biosynth

Chemical properties

• Molecular weight: 152.23 g/mol
• Formula: C₁₀H₁₆O
• Purity: Min. 90%
• Color/Form: Clear Liquid
• InChI: InChI=1S/C10H16O/c1-8(2)10-5-3-9(7-11)4-6-10/h3,10-11H,1,4-7H2,2H3
• InChI key: InChIKey=NDTYTMIUWGWIMO-UHFFFAOYSA-N
• SMILES: C=C(C)C1CC=C(CO)CC1