5-Phenylpenta-2,4-dienoic acid

CAS: 1552-94-9

Ref. 3D-FP70999

Product Information

• Name: 5-Phenylpenta-2,4-dienoic acid
• Synonyms: Cinnamylidene acetic acid, 1-Carboxy-4-phenyl-1,3-butadiene, 1-Carobxy-4-phenyl-1,3-butadiene, 2,4-Pentadienoic acid, 5-phenyl-, 5-Phenyl-2,4-pentadienoic acid, 5-Phenylpenta-2,4-Dienoic Acid, Bl 1255, Cinnamalacetic acid, Cinnamylideneacetic acid, NSC 109408, NSC 1778, NSC 63972, β-Styrylacrylic acid

Description

5-Phenylpenta-2,4-dienoic acid is a high-potency inhibitor of tyrosine kinases. It has been shown to have an inhibitory effect on cancer cells in both squamous and non-squamous cell lines. This compound has been shown to inhibit the proliferation of cancer cells by arresting cell cycle progression at the G1 phase, which leads to the inhibition of DNA synthesis. 5-Phenylpenta-2,4-dienoic acid is also able to block the activation of transcription factors that are involved in tumorigenesis. In addition, this compound inhibits the proliferation of cancer cells by arresting cell cycle progression at the G1 phase, leading to inhibition of DNA synthesis. The molecular modeling study suggests that this compound may be able to bind with tyrosine kinase receptors on the surface of tumor cells and block their activity. The chemical structure of 5-phenylpenta-2,4-dien

• Brand: Biosynth

Chemical properties

• Molecular weight: 174.2 g/mol
• Formula: C₁₁H₁₀O₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C11H10O2/c12-11(13)9-5-4-8-10-6-2-1-3-7-10/h1-9H,(H,12,13)/b8-4+,9-5+
• InChI key: InChIKey=FEIQOMCWGDNMHM-KBXRYBNXSA-N
• SMILES: O=C(O)/C=C/C=C/c1ccccc1