N-[(2Z)-Piperazin-2-ylidene]-2,2,2-trifluoroacetohydrazide

CAS: 849832-73-1

Ref. 3D-FP95705

Product Information

• Name: N-[(2Z)-Piperazin-2-ylidene]-2,2,2-trifluoroacetohydrazide
• Brand: Biosynth
• Description: N-[(2Z)-Piperazin-2-ylidene]-2,2,2-trifluoroacetohydrazide (NPI) is a hydrazine derivative with cyclization and chlorination. It is an oxychloride of N-(2-chloroethyl)hydrazinecarbothioamide. Hydrazine derivatives are mainly used as synthetic intermediates for the production of pharmaceuticals and agrochemicals. Trifluoroacetate is a chemical compound that has been shown to be active against the growth of Mycobacterium tuberculosis and Mycobacterium avium complex. Trifluoroacetate inhibits the biosynthesis of mycolic acids, which are essential components of the cell wall in these bacteria. The mechanism of action of trifluoroacetate involves inhibition of the enzyme mycolic acid synthase through covalent modification by forming an adduct with its active site cysteine residue.

Chemical properties

• Molecular weight: 210.16 g/mol
• Formula: C₆H₉F₃N₄O
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C6H9F3N4O/c7-6(8,9)5(14)13-12-4-3-10-1-2-11-4/h10H,1-3H2,(H,11,12)(H,13,14)
• InChI key: InChIKey=RKIDLJBEMIARHI-UHFFFAOYSA-N
• SMILES: O=C(NNC1=NCCNC1)C(F)(F)F