2-Quinolinecarboxylic acid

CAS: 93-10-7

Ref. 3D-FQ10003

Product Information

• Name: 2-Quinolinecarboxylic acid
• Synonyms: Quinaldic acidQuinoline-2-carboxylic acid
• Brand: Biosynth

Description

2-Quinolinecarboxylic acid is an antibiotic that is used in the treatment of bacterial infections and has inhibitory properties. It has been shown to be a competitive inhibitor of the enzyme quinolinate phosphoribosyltransferase, which catalyzes the conversion of quinolinic acid to nicotinic acid. 2-Quinolinecarboxylic acid binds to the active site of the enzyme and prevents substrate binding, thereby blocking the production of nicotinic acid. This drug also inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucur

Chemical properties

• Molecular weight: 173.17 g/mol
• Formula: C₁₀H₇NO₂
• Purity: Min. 98 Area-%
• Color/Form: Powder