Qingdainone

CAS: 97457-31-3

Ref. 3D-FQ65726

Product Information

• Name: Qingdainone
• Synonyms: Candidine, indolo[2,1-b]quinazolin-12(6H)-one, 6-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-, (6E)-

Description

Qingdainone is a natural compound that can be extracted from the roots of Polygonum cuspidatum. It has been shown to have anti-inflammatory and immunomodulatory properties. Qingdainone has demonstrated its activity against inflammatory bowel disease, with a dose-dependent pattern. The compound is able to induce tissue antigens by suppressing inflammatory cytokines in intestinal epithelial cells. Qingdainone has also been shown to inhibit the growth of several types of bacteria, including Staphylococcus aureus, through inhibition of DNA gyrase and topoisomerase IV. This inhibition leads to cell death by inhibiting protein synthesis, which is vital for cell division.

• Brand: Biosynth

Chemical properties

• Molecular weight: 363.37 g/mol
• Formula: C₂₃H₁₃N₃O₂
• Purity: 90%
• Color/Form: Powder
• InChI: InChI=1S/C23H13N3O2/c27-21-13-7-1-4-10-16(13)24-20(21)19-15-9-3-6-12-18(15)26-22(19)25-17-11-5-2-8-14(17)23(26)28/h1-12,24H/b20-19+
• InChI key: InChIKey=DXENDDMPDZMHSQ-FMQUCBEESA-N
• SMILES: O=C1/C(=c2/c3ccccc3n3c(=O)c4ccccc4nc23)Nc2ccccc21