Quinoline 2,4-dicarboxylic acid

CAS: 5323-57-9

Ref. 3D-FQ67149

Product Information

• Name: Quinoline 2,4-dicarboxylic acid
• Brand: Biosynth

Description

Quinoline 2,4-dicarboxylic acid (QDA) is a novel cytotoxic agent that targets cervical cancer cells. It inhibits the uptake of glucose and other nutrients by cervical cancer cells, leading to cell death through apoptosis. QDA also inhibits the expression of genes involved in cross-linking reactions, which are important for the structural integrity of proteins. This agent has been shown to inhibit the growth of aniline-induced breast cancer cells and glutamate-stimulated PC12 cells. QDA binds to DNA and forms covalent bonds with nucleotide bases, inhibiting DNA synthesis, as well as interfering with protein synthesis and cell division. The QDA mechanism is similar to that of benzoquinolines and estrone sulfate.

Chemical properties

• Molecular weight: 217.18 g/mol
• Formula: C₁₁H₇NO₄
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C11H7NO4/c13-10(14)7-5-9(11(15)16)12-8-4-2-1-3-6(7)8/h1-5H,(H,13,14)(H,15,16)
• InChI key: InChIKey=JPGZDTDZZDLVHW-UHFFFAOYSA-N
• SMILES: O=C(O)c1cc(C(=O)O)c2ccccc2n1