Rutaecarpine

CAS: 84-26-4

Ref. 3D-FR09427

Product Information

• Name: Rutaecarpine
• Synonyms: 3,13,21-Triazapentacyclo[11.8.0.0[2,10].0[4,9].0[15,20]]henicosa-1(21),2(10),4(9),5,7,15(20),16,18-octaen-14-one, 8,13,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one, 8,13-Dihydroindolo[2′,3′:3,4]pyrido[2,1-b]quinazolin-5(7H)-one, Indolo[2′,3′:3,4]pyrido[2,1-b]quinazolin-5(7H)-one, 8,13-dihydro-, NSC 258317, Rhetine

Description

Rutaecarpine is a natural product that is extracted from the roots of Rutaceae plants. It has been shown to inhibit ATP-binding cassette transporters, which are involved in intestinal absorption of dietary lipids and cholesterol, as well as intracellular calcium levels. Rutaecarpine also inhibits the activity of pyrazole ring cyclase, which is responsible for the synthesis of prostaglandins, including thromboxane A2. This inhibition leads to reduced inflammation in the bowel and attenuates neuronal death caused by brain injury. Injection solutions containing rutaecarpine have been shown to be effective against nonsteroidal anti-inflammatory drugs (NSAIDs) such as indomethacin and ibuprofen in animal models.

• Brand: Biosynth

Chemical properties

• Molecular weight: 287.32 g/mol
• Formula: C₁₈H₁₃N₃O
• Purity: Min. 95%
• InChI: InChI=1S/C18H13N3O/c22-18-13-6-2-4-8-15(13)20-17-16-12(9-10-21(17)18)11-5-1-3-7-14(11)19-16/h1-8,19H,9-10H2
• InChI key: InChIKey=ACVGWSKVRYFWRP-UHFFFAOYSA-N
• SMILES: O=c1c2ccccc2nc2n1CCc1c-2[nH]c2ccccc12