Rauwolscine hydrochloride

CAS: 6211-32-1

Ref. 3D-FR145191

Product Information

• Name: Rauwolscine hydrochloride
• Synonyms: (16Beta,17Alpha,20Alpha)-17-Hydroxy-16-(Methoxycarbonyl)Yohimban-4-Ium, 20α-Yohimban-16β-carboxylic acid, 17α-hydroxy-, methyl ester, monohydrochloride, Methyl (16Beta,17Alpha,20Alpha)-17-Hydroxyyohimban-16-Carboxylate, Methyl (16Beta,17Alpha,20Alpha)-17-Hydroxyyohimban-16-Carboxylate Hydrochloride (1:1), Methyl (16Beta,20Alpha)-17-Hydroxyyohimban-16-Carboxylate, Methyl (17Alpha,20Alpha)-17-Hydroxyyohimban-16-Carboxylate Hydrochloride, NSC 407307, Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, hydrochloride (1:1), (16β,17α,20α)-, Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, monohydrochloride, (16β,17α,20α)-, α-Yohimbine hydrochloride

Description

Rauwolscine hydrochloride is a potent antagonist of the 5-HT2 receptor. It has been shown to inhibit the replication of HIV in tissue culture and to block the binding of 5-HT to its receptor. Rauwolscine hydrochloride also blocks 5-HT7 receptors, which are found in gland cells and have been implicated in infectious diseases. Rauwolscine hydrochloride has shown to inhibit mitochondrial activity when injected into the femoral vein of rats. This inhibition was shown to be due to a direct interaction with mitochondrial inhibitors such as cytochrome C oxidase, succinate dehydrogenase, and adenylate kinase. The drug has been shown to bind selectively with high affinity to rat brain 5-HT2 receptors in the caudate putamen region of the brain and also inhibits lacrimal gland secretion. Rauwolscine hydrochloride has also been tested on skin models for its potential as an

• Brand: Biosynth

Chemical properties

• Molecular weight: 390.9 g/mol
• Formula: C₂₁H₂₆N₂O₃·HCl
• Purity: Min. 95%
• Color/Form: Powder