Resiquimod

CAS: 144875-48-9

Ref. 3D-FR170507

Product Information

• Name: Resiquimod
• Synonyms: 1-[4-Amino-2-(ethoxymethyl)imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol, 1H-Imidazo[4,5-c]quinoline-1-ethanol, 4-amino-2-(ethoxymethyl)-α,α-dimethyl-, 4-Amino-2-(ethoxymethyl)-1-(2-hydroxyisobutyl)imidazo[4,5-c]quinoline, 4-Amino-2-(ethoxymethyl)-alpha,alpha-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol, 4-Amino-2-(ethoxymethyl)-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol, R-848, Resimiquimod, S-28463, Vml-600
• CAS: 144875-48-9

Description

Resiquimod is a synthetic imidazoquinoline that has potent immunological activities, including induction of cytokines and chemokines. It is capable of activating the immune system by binding to toll-like receptor 7 (TLR-7) and TLR8, which are receptors expressed on dendritic cells, macrophages and other antigen-presenting cells. Resiquimod can also activate the immune system by activating cell factor, a protein found in white blood cells that plays an important role in the activation of T lymphocytes. In vitro assays have shown that resiquimod has strong antiviral properties against HIV-1 and HIV-2, as well as anti-cancer properties against skin cancer. Resiquimod’s ability to induce cytokines and chemokines makes it a good candidate for treating autoimmune diseases such as psoriasis or rheumatoid arthritis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 314.38 g/mol
• Formula: C₁₇H₂₂N₄O₂
• Purity: Min. 98 Area-%
• Color/Form: White Powder
• InChI: InChI=1S/C17H22N4O2/c1-4-23-9-13-20-14-15(21(13)10-17(2,3)22)11-7-5-6-8-12(11)19-16(14)18/h5-8,22H,4,9-10H2,1-3H3,(H2,18,19)
• InChI key: InChIKey=BXNMTOQRYBFHNZ-UHFFFAOYSA-N
• SMILES: CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)O