rac-5,6,7,8-tetrahydro-6-(propylamino)-1-naphthalenol

CAS: 78950-82-0

Ref. 3D-FR27619

Product Information

• Name: rac-5,6,7,8-tetrahydro-6-(propylamino)-1-naphthalenol
• Synonyms: 5-Hydroxy-2-(N-propyl)-aminotetralin
• CAS: 78950-82-0

Description

Rotigotine is a substance that belongs to the class of active compounds. It has been shown to have optical activity, but this property is not well understood. Rotigotine is a racemic mixture with two enantiomers, which are mirror images of each other. The optical rotation of rac-5,6,7,8-tetrahydro-6-(propylamino)-1-naphthalenol is given as +28°. This property can be determined by measuring the angle of rotation when light passes through the substance in solution in contact with a polarizer and analyzer.

Rotigotine is an effective treatment for Parkinson's disease and has been approved for use in Europe since 1999. The drug binds to dopamine receptors in the brain and selectively inhibits catecholamine uptake into presynaptic neurons, thereby increasing dopamine levels in these cells and providing relief from symptoms of Parkinson's disease. In addition to its effect on dopaminergic transmission, rot

• Brand: Biosynth

Chemical properties

• Molecular weight: 205.3 g/mol
• Formula: C₁₃H₁₉NO
• Purity: Min. 95%
• InChI: InChI=1S/C13H19NO/c1-2-8-14-11-6-7-12-10(9-11)4-3-5-13(12)15/h3-5,11,14-15H,2,6-9H2,1H3
• InChI key: InChIKey=VCYPZWCFSAHTQT-UHFFFAOYSA-N
• SMILES: CCCNC1CCc2c(O)cccc2C1