Rhynchophylline

CAS: 76-66-4

Ref. 3D-FR42770

Product Information

• Name: Rhynchophylline
• Synonyms: Corynoxan-16-carboxylic acid, 16,17-didehydro-17-methoxy-2-oxo-, methyl ester, (7β,16E,20α)-, Mitrinermin, Mitrinermine, NSC 21731, Rhyncholphylline, Rhynchophyllin, Rhyncophylline, Spiro[3H-indole-3,1′(5′H)-indolizine]-7′-acetic acid, 6′-ethyl-1,2,2′,3′,6′,7′,8′,8′a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, (αE,1′R,6′R,7′S,8′aS)-, Spiro[3H-indole-3,1′(5′H)-indolizine]-7′-acetic acid, 6′-ethyl-1,2,2′,3′,6′,7′,8′,8′a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, [1′R-[1′α,6′β,7′α(E),8′aβ]]-, methyl (16Z)-16-(methoxymethylidene)-2-oxocorynoxan-17-oate, methyl (3xi,16E,20alpha)-16-(methoxymethylidene)-2-oxocorynoxan-17-oate, methyl (3xi,16Z,20alpha)-16-(methoxymethylidene)-2-oxocorynoxan-17-oate, methyl (7beta,16E,20alpha)-16-(methoxymethylidene)-2-oxocorynoxan-17-oate

Description

Rhynchophylline is a plant alkaloid that belongs to the group of indole alkaloids. It has been found to inhibit the production of proinflammatory cytokines and growth factor-β1 in hl-60 cells. Rhynchophylline also inhibits neuronal death induced by lipopolysaccharide and prevents disease activity in mice with collagen-induced arthritis. Rhynchophylline has been shown to have synergistic effects with isocorynoxeine, an anti-inflammatory drug, which may be due to its ability to inhibit P-glycoprotein (Pgp), a protein that transports a wide range of substrates across cellular membranes.

• Brand: Biosynth

Chemical properties

• Molecular weight: 384.47 g/mol
• Formula: C₂₂H₂₈N₂O₄
• Purity: Min. 95%
• Color/Form: Powder