R-Reticuline

CAS: 3968-19-2

Ref. 3D-FR76328

Product Information

• Name: R-Reticuline
• Synonyms: (-)-Reticuline, 7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methyl-, (1R)-, L-Reticuline, (1R)-1,2,3,4-Tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methyl-7-isoquinolinol, 7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methyl-, (R)-

Description

R-Reticuline is a natural compound that has been shown to be an effective inhibitor of the enzyme cyclooxygenase-2 (COX-2). It binds to the active site of COX-2 and blocks the conversion of arachidonic acid to prostaglandin H2, thereby inhibiting inflammation. R-Reticuline can also inhibit other enzymes in the same family, such as lipooxygenase and 5-lipoxygenase. The COX-2 inhibition by R-Reticuline may be due to its ability to bind to a receptor on cells, which leads to inhibition of transcriptional activation.

• Brand: Biosynth

Chemical properties

• Molecular weight: 329.39 g/mol
• Formula: C₁₉H₂₃NO₄
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C19H23NO4/c1-20-7-6-13-10-19(24-3)17(22)11-14(13)15(20)8-12-4-5-18(23-2)16(21)9-12/h4-5,9-11,15,21-22H,6-8H2,1-3H3/t15-/m1/s1
• InChI key: InChIKey=BHLYRWXGMIUIHG-OAHLLOKOSA-N
• SMILES: COc1ccc(C[C@@H]2c3cc(O)c(OC)cc3CCN2C)cc1O