Ralfinamide

Ref. 3D-FR98311

Product Information

• Name: Ralfinamide
• Brand: Biosynth
• Description: Ralfinamide is a potent and selective blocker of the neuronal sodium channel. It has been shown to inhibit viral replication in cells infected with HIV-1, HSV-2, and vesicular stomatitis virus. Ralfinamide also produces a dose-dependent inhibition of rotarod performance in mice and inhibits acid formation in rat stomachs. This drug has been shown to have pressor effects at high doses and causes whole-cell recordings from neurons to be more sensitive to depolarization by an increase in intracellular chloride ions. Ralfinamide mesylate is a crystalline polymorph that is more soluble than ralfinamide hydrochloride, making it more suitable for oral administration.

Chemical properties

• Molecular weight: 302.34 g/mol
• Formula: C₁₇H₁₉FN₂O₂
• Purity: Min. 95%