Sulphanilamide

CAS: 63-74-1

Ref. 3D-FS07881

Product Information

• Name: Sulphanilamide
• Synonyms: p-Aminobenzenesulfonamide, (4-(Aminosulfonyl)phenyl)amine, 1162F, 4-(Aminosulfonyl)aniline, 4-Aminobenzene-1-sulfonamide, 4-Aminobenzenesulfonamide, 4-Aminophenylsulfonamide, 4-Aminosulfoneamide, 4-Sulfamoylaniline, A-349, AVC, Albexan, Albosal, Ambeside, Aminobenzenesulfonamide, Antistrept, Astreptine, Astrocid, Bacteramid, Bactesid, Collomide, Colsulanyde, Copticide, Deseptyl, Dipron, Ergaseptine, Erysipan, Estreptocida, Exoseptoplix, Gerison, Gombardol, Infepan, Lusil, Lysococcine, Neococcyl, Orgaseptine, P-Aminophenylsulfonamide, Pabs, Prontalbin, Prontylin, Proseptal, Proseptine, Proseptol, Pysococcine, Sanamid, Septanilam, Septinal, Septolix, Septoplex, Septoplix, Stramid, Strepamide, Strepsan, Streptagol, Streptamid, Streptasol, Streptocid, Streptocide, Streptoclase, Streptocom, Streptol, Strepton, Streptopan, Streptosil, Streptozol, Streptozone, Streptrocide, Sulfamidyl, Sulfamine, Sulfana, Sulfanalone, Sulfanidyl, Sulfanil, Sulfanilamid, Sulfanilamida, Sulfanilimide, Sulfocidine, Sulfonamid, Sulfonamide, Sulfonylamide, Sulphonamide, Therapol, Tolder, Vagitrol, p-Anilinesulfonamide, p-Sulfamidoaniline, p-Sulfamoylaniline

Description

Sulphanilamide is an antimicrobial agent that inhibits the growth of bacteria by binding to their enzymes and blocking protein synthesis. In addition, sulphanilamide has been shown to inhibit the production of sulfanilamide, a potent inhibitor of tetracycline. Sulphanilamide is soluble in water and alcohol but not in organic solvents. The solubility of sulphanilamide can be increased by adding sodium salts or pH adjustment. Sulphanilamide is also used for wastewater treatment as it has inhibitory properties against sulfate-reducing bacteria. X-ray crystal structures have revealed that sulphanilamide binds to the active site of bacterial beta-lactamases through hydrogen bonds with both the NH group and the COOH group on its sulfur atom, resulting in inhibition of these enzymes. Sulphanilamide also interferes with bacterial DNA replication by inhibiting dna gyrase and topoisomerase IV. Sulphanilamide also

• Brand: Biosynth

Chemical properties

• Molecular weight: 172.21 g/mol
• Formula: C₆H₈N₂O₂S
• Color/Form: Powder
• InChI: InChI=1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)
• InChI key: InChIKey=FDDDEECHVMSUSB-UHFFFAOYSA-N
• SMILES: Nc1ccc(S(N)(=O)=O)cc1