SPARC (119-122) (mouse) acetate salt
CAS: 155149-79-4
Ref. 3D-FS108680
25mg | 292.00 € | ||
50mg | 477.00 € | ||
100mg | 737.00 € | ||
250mg | 1,328.00 € | ||
500mg | 2,308.00 € |
Product Information
- H-Lys-Gly-His-Lys-OH H-KGHK-OH
SPARC (119-122) (mouse) is an acetate salt of H-Lys-Gly-His-Lys-OH. SPARC (119-122) has been shown to be a mimetic of the c-terminal region of the protein SPARC and can bind to many metal ions including Zn2+, Mn2+, Cu2+, Co2+, Ni2+ and Mg2+. The binding affinity for these metals is dose dependent, with saturation occurring at high concentrations. This property may make this compound a therapeutic target for drug discovery strategies.
SPARC (119-122) has been shown to inhibit lisinopril, an angiotensin converting enzyme inhibitor that is used as a drug to treat hypertension and heart failure. Lisinopril inhibits the conversion of angiotensin I into angiotensin II which causes vasoconstriction and increases blood pressure. In in vitro studies, SPARC (119-122)
Chemical properties
Technical inquiry about: 3D-FS108680 SPARC (119-122) (mouse) acetate salt
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