H-Ser-Glu-Gly-OH

CAS: 67509-32-4

Ref. 3D-FS109421

Product Information

• Name: H-Ser-Glu-Gly-OH
• Brand: Biosynth
• Description: H-Ser-Glu-Gly-OH is an atypical compound that has shown anti-cancer activity in vitro. It is a member of the family of compounds known as glycine receptor antagonists. H-Ser-Glu-Gly-OH has been shown to inhibit the proliferation of A549 lung cancer cells and to induce cell cycle arrest and apoptosis. The compound also inhibits the activation of signal regulated kinase (ERK) in A549 lung cancer cells, which may be due to its ability to inhibit the production of cytokines such as IL6, IL8, and TNFα. H-Ser-Glu-Gly-OH also has mitogenic and antiproliferative activities for a variety of nonmalignant cell lines including human umbilical vein endothelial cells (HUVEC), human embryonic kidney cells (HEK293), and mouse erythroleukemia cells (MEL).

Chemical properties

• Molecular weight: 291.26 g/mol
• Formula: C₁₀H₁₇N₃O₇
• Purity: Min. 95%
• InChI: InChI=1S/C10H17N3O7/c11-5(4-14)9(19)13-6(1-2-7(15)16)10(20)12-3-8(17)18/h5-6,14H,1-4,11H2,(H,12,20)(H,13,19)(H,15,16)(H,17,18)/t5-,6-/m0/s1
• InChI key: InChIKey=YRBGKVIWMNEVCZ-WDSKDSINSA-N
• SMILES: N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)O