3D-FS137720 - ssr128129e
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SSR128129E
CAS:SSR128129E (SSR) is an allosteric and orally-active FGFR1 inhibitor (IC50: 1.9 μM), but not affecting other related RTKs.Formula:C18H15N2O4·NaPurity:98.79% - ≥95%Color and Shape:SolidMolecular weight:346.31SSR128129E
CAS:Controlled ProductApplications SSR128129E (SSR) is an potent FGFR inhibitor, which inhibits fibroblast growth factor receptor (FGFR). Oral delivery of SSR128129E inhibits arthritis and tumors that are relatively refractory to anti-vascular endothelial growth factor receptor-2 antibodies.
References Bono, F., et al.: Cancer Cell., 23, 477 (2013); Dol-Gleizes, F., et al.: PLoS One, 8, e80027 (2013)Formula:C18H15N2NaO4Color and Shape:Yellowish SolidMolecular weight:346.31SSR128129E free acid
CAS:SSR128129E free acid is an orally available and allosteric inhibitor of FGFR(IC50 of 1.9 μM for FGFR1).Formula:C18H16N2O4Purity:98%Color and Shape:SolidMolecular weight:324.33Sodium 2-Amino-5-(1-Methoxy-2-Methylindolizine-3-Carbonyl)Benzoate
CAS:Sodium 2-Amino-5-(1-Methoxy-2-Methylindolizine-3-Carbonyl)BenzoatePurity:99%Molecular weight:346.31g/mol
