Sitagliptin phosphate monohydrate

CAS: 654671-77-9

Ref. 3D-FS159000

Product Information

• Name: Sitagliptin phosphate monohydrate
• Brand: Biosynth
• Description: Sitagliptin phosphate monohydrate is a DPP-IV inhibitor that is used to treat type 2 diabetes mellitus. Sitagliptin decreases postprandial glucose levels and improves glycemic control. It binds to the enzyme DPP-IV, which breaks down peptides in the small intestine, inhibiting the breakdown of incretin hormones such as glucagon-like peptide 1 and glucose transporter type 2 (GLUT2). This leads to increased levels of GLP-1. Sitagliptin also has been shown to have an anti-diabetic effect by increasing insulin release from pancreatic beta cells.

Chemical properties

• Molecular weight: 523.32 g/mol
• Formula: C₁₆H₂₀F₆N₅O₆P
• Purity: Min. 95%
• Color/Form: White Powder