Senecionine N-oxide
CAS: 13268-67-2
Ref. 3D-FS161594
1mg | 236.00 € | ||
2mg | 354.00 € | ||
5mg | 569.00 € | ||
10mg | 867.00 € | ||
25mg | 1,578.00 € |
Product Information
- (1,6)Dioxacyclododecino(2,3,4-gh)pyrrolizine-3,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl-, 12-oxide, (3Z,5R,6R,14aR,14bR)-
- (3E,5R,6R,14aR,14bR)-3-ethylidene-6-hydroxy-5,6-dimethyl-3,4,5,6,9,11,13,14,14a,14b-decahydro[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione 12-oxide
- (5R,6R,14aR,14bR)-3-ethylidene-6-hydroxy-5,6-dimethyl-3,4,5,6,9,11,13,14,14a,14b-decahydro[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione 12-oxide
- 12-Hydroxysenecionan-11,16-dione 4-oxide
- Nsc 106677
- Senecionan-11,16-dione, 12-hydroxy-, 4-oxide
- Senecionine oxide
- [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl-, 12-oxide, (3Z,5R,6R,14aR,14bR)-
- [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl-, 12-oxide, (3Z,5R,6R,14aR,14bR)-[partial]-
Senecionine N-oxide is a natural product that has been shown to have strong cytotoxic effects on cultured liver cells. It is a metabolite of retrorsine and senecionine, which are quinolizidine alkaloids found in plants of the genus Senecio. The presence of the hydroxyl group in senecionine N-oxide makes it more reactive than its parent compounds. This leads to metabolic changes, including an increase in metabolic rate and dose-dependent effects. Senecionine N-oxide also has a high molecular weight, which makes it difficult to measure using analytical methods such as HPLC or GCMS. To overcome this challenge, researchers use sample preparation techniques like thin layer chromatography (TLC) or liquid chromatography (LC). Tissue culture experiments have shown that senecionine N-oxide has biological properties similar to retrorsine and can induce cell death by inhibiting DNA synthesis.
Chemical properties
Technical inquiry about: 3D-FS161594 Senecionine N-oxide
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.