Product Information
- (3beta,5alpha,7alpha,24R)-3-({3-[(4-aminobutyl)amino]propyl}amino)-7-hydroxycholestan-24-yl hydrogen sulfate
- (3β,5α,7α)-3-[[3-((4-Aminobutyl)amino)propyl]amino]cholestane-7,24-diol-24-hydrogen sulfate
- Cholestane-7,24-diol, 3-[[3-[(4-aminobutyl)amino]propyl]amino]-, 24-(hydrogen sulfate), (3β,5α,7α,24R)-
- Msi 1256
Squalamine is a drug that has been shown to have in vitro antifungal activity against Candida albicans. Squalamine also has in vitro antibacterial efficacy against gram-positive species, such as Streptococcus pneumoniae and Staphylococcus aureus.
In vivo studies have been performed using the squalamine analogue, SSQ-5, which is an active compound of squalamine. The SSQ-5 analogue was shown to be toxic against human carcinoma cells and was effective in combination therapy with polymyxin B for the treatment of Gram-negative infections.
Chemical properties
Technical inquiry about: 3D-FS162105 Squalamine
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