4-Methoxy-4-oxobutanoic acid

CAS: 3878-55-5

Ref. 3D-FS163512

Product Information

• Name: 4-Methoxy-4-oxobutanoic acid
• Synonyms: Monomethyl succinate 3-(Methoxycarbonyl)propanoic acid Succinic acid monomethyl ester, 1,4-Butanedioic acid monomethyl ester, 3-(Methoxycarbonyl)propanoic acid, 3-(Methoxycarbonyl)propionic acid, 3-Carbomethoxypropanoic acid, 4-Methoxy-4-Oxobutanoate, Butanedioic acid, 1-methyl ester, Butanedioic acid, monomethyl ester, Fema Gras 3810, Methyl Hydrogen Succinate, Methyl monosuccinate, Monomethyl butanedioate, Monomethyl succinate, NSC 511, Succinic acid monomethyl ester, Succinic acid, methyl ester, mono-Methyl hydrogen succinate
• CAS: 3878-55-5

Description

Succinic acid monomethyl ester (SAMME) is an antimicrobial agent that inhibits the enzyme activities of succinate dehydrogenase, producing mitochondrial membrane depolarization and neuronal death. SAMME has been shown to be effective in treating syncytial virus infection and solid tumours, although it has not been studied in depth. The biological sample used for this study was water vapor, which is a substrate molecule for the enzyme succinic acid semialdehyde dehydrogenase (SASD). This enzyme converts SAMME to succinic acid, which can then inhibit phosphofructokinase-1 or pyruvate kinase, leading to cellular necrosis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 132.11 g/mol
• Formula: C₅H₈O₄
• Purity: Min. 95%
• InChI: InChI=1S/C5H8O4/c1-9-5(8)3-2-4(6)7/h2-3H2,1H3,(H,6,7)
• InChI key: InChIKey=JDRMYOQETPMYQX-UHFFFAOYSA-N
• SMILES: COC(=O)CCC(=O)O